Oral Oncolytic Agents—A Need for Research to Enhance Patient Centeredness?

Empathy for Patient Centeredness and Patient Empowerment

Empathy involve internal process of experiencing what is perceived from the outside world through our senses leading to imaginations and projections, so that such experience will turn the belief of “I and you” in to “I am you” or at least “I might be you”. According to Hojat, empathy in clinical practice is predominantly a cognitive attribute that involves understanding and communicating this u...

Need to define patient engagement in research.

Current Immunotherapeutic Strategies to Enhance Oncolytic Virotherapy

Oncolytic viruses (OV) represent a promising strategy to augment the spectrum of cancer therapeutics. For efficacy, they rely on two general mechanisms: tumor-specific infection/cell-killing, followed by subsequent activation of the host's adaptive immune response. Numerous OV genera have been utilized in clinical trials, ultimately culminating in the 2015 Food and Drug Administration approval ...

Preexposure Prophylaxis and Patient Centeredness

Preexposure prophylaxis has transformed HIV prevention, becoming widespread in communities of gay and bisexual men in the developed world in a short time. There is a broad concern that preexposure prophylaxis will discourage condom use among gay men (i.e., "risk compensation"). This commentary argues for broadening the focus on gay men's health beyond sexual health to address the holistic healt...

Patient and plan characteristics affecting abandonment of oral oncolytic prescriptions.

OBJECTIVE To calculate the abandonment rate of oral oncolytic medications and identify factors that may affect likelihood of abandonment. STUDY DESIGN Cross-sectional cohort study using administrative claims data. METHODS We analyzed a nationally representative pharmacy claims database and identified 10,508 patients with Medicare and commercial insurance for whom oral oncolytic therapy was ...